Journal: Nucleic Acids Research
Article Title: Genome-wide chromosomal association of Upf1 is linked to Pol II transcription in Schizosaccharomyces pombe
doi: 10.1093/nar/gkab1249
Figure Lengend Snippet: Significant overlap between genes bound by Upf1 and genes differentially expressed in a upf1 Δ strain. ( A ) Venn diagram showing the overlap between the genes/genomic regions strongly associated with Upf1 (420, identified using the P -value cut off of 10 –4 in the MAT software) and differentially expressed genes in upf1 Δ (543). The asterisk indicates that the P -value of this overlap is either 0.001 based on random sampling, or of 0.006 based on a Fisher's exact hypergeometric test (Material and Methods). ( B ) List of the 47 overlapping genes. Genes highlighted in red are up-regulated and genes highlighted in green are down-regulated. Genes which were tested and show increased Ser2 CTD phosphorylation are shown with their full names in blue.
Article Snippet: We used the Model-based Analysis of Tiling Arrays (MAT) software to analyse the Affymetrix hybridization data ( ).
Techniques: Software, Sampling